Welcome to the Kleanthous Lab


Protein-protein interactions in the Gram-negative bacterial cell envelope

In my laboratory, we aim to understand how protein-protein interactions in bacteria help support the organisation, structure and stability of the outer membrane and how such interactions can also be exploited by protein antibiotics known as bacteriocins to kill bacterial cells. Our research typically incorporates a range of biochemical, biophysical, structural and cell-based techniques. Our work is supported by the Wellcome Trust, ERC and BBSRC.